Description
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Material: Doxycycline Hyclate |
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CAS No.: 24390-14-5 |
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ITEM |
STANDARD |
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Appearance |
Yellow crystalline powder |
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Solubility |
Freely soluble in water and in methanol, sparingly soluble in ethanol. It dissolves in solutions of alkalihydroxides and carbonates. |
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Identification |
HPLC |
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Sulphuric acid reaction a yellow colour develops |
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It gives reaction of chlorides |
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PH |
2.0~3.0 |
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Specific Absorbance (349nm) |
E(1%) 300~335 |
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Specific optical rotation |
-120°~-105° |
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Heavy Metal |
≤50ppm |
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Light-adsorbing impurities |
At 490nm ≤0.07 |
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Related Substances
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a 6-epidoxycycline ≤2.0% |
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b metacycline ≤2.0% |
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c 4-epidoxycycline ≤0.5% |
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d 4-epi-6-epidoxycycline ≤0.5% |
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e oxytetracycline ≤0.5% |
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f 2-acety-2-decarbamoyldoxycycline ≤0.5% |
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g any unspecified impurity ≤0.1% |
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Ethanol |
4.3~6.0% (m/m) |
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Sulphated ash |
≤0.4% |
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Mositure |
1.4~2.8% |
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Assay |
95.0~102.0% |
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Conclusion: |
The above product conforms toEP8.0&BP2014 Standard. |
