Description
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Material: Ticagrelor |
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CAS No.: 274693-27-5 |
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ITEM |
STANDARD |
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Appearance |
White to off-white powder |
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Solubility |
Freely soluble in Methanol and Acetone. |
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Melting Point ℃ |
137~143 |
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Identification |
IR & HPLC |
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Specific optical rotation ° |
-50~-60 |
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Loss on drying % |
≤0.50 |
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Residue on ignition % |
≤0.10 |
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Heavy metals ppm |
<20ppm |
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Isomers % |
TGD1≤0.15 |
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TGD2≤0.15 |
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TGE≤0.15 |
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Related Substance % |
TG-16≤0.15 |
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De-ethoxyl of TG ≤0.15 |
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Any individual impurity ≤0.10 |
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Total impurities ≤1.0 |
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Residual Solvents |
Methanol ≤3000ppm |
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Ethanol ≤5000ppm |
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Ethyl ether ≤5000ppm |
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Acetone ≤5000ppm |
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Acetonitrile ≤410ppm |
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Dichloromethane ≤600ppm |
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n-Hexane ≤290ppm |
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Assay (Calculated on the dried basis) % |
98.0~102.0 |
